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Aging is Now Optional w/ David Sinclair | EP #60
Advancements in genetic engineering, gene therapies, and anti-aging research may eventually allow for age reversal and the restoration of youthful health and longevity. What is the key idea of the video? —The key idea is that advancements in genetic engineering and anti-aging research may eventually allow for age reversal and the restoration of youthful health and longevity. How can aging be reversed? —Aging can be reversed through rejuvenating the brain, restoring memories and learning abilities, and addressing the loss of inherited information through genetic engineering and epigenetic reprogramming. Is there an upper limit to human aging? —No, there is no...
𝐒𝐜𝐢𝐞𝐧𝐭𝐢𝐬𝐭𝐬 𝐂𝐫𝐞𝐚𝐭𝐞 𝐀𝐫𝐭𝐢𝐟𝐢𝐜𝐢𝐚𝐥 𝐌𝐢𝐭𝐨𝐜𝐡𝐨𝐧𝐝𝐫𝐢𝐚 𝐓𝐡𝐚𝐭 𝐂𝐚𝐧 𝐌𝐚𝐤𝐞 𝐄𝐧𝐞𝐫𝐠𝐲 𝐟𝐨𝐫 𝐃𝐚𝐦𝐚𝐠𝐞𝐝 𝐂𝐞𝐥𝐥𝐬
Mitochondrial decay due to oxidant byproducts is a principal underlying contributor to aging, including the degenerative diseases of aging such as brain degeneration. The energy for basic metabolic processes comes from mitochondria, and their decay with age impairs cellular metabolism and leads to cellular decline. Oxidants generated by mitochondria appear to be the major source of the oxidative lesions that accumulate with age. Evidence supports the suggestion that age-associated accumulation of mitochondrial deficits due to oxidative damage is likely to be a major contributor to cellular, tissue, and organismal aging. Can we create artificial mitochondria? This recent article...
𝐒𝐜𝐢𝐞𝐧𝐭𝐢𝐬𝐭𝐬 𝐮𝐧𝐥𝐨𝐜𝐤 𝐠𝐞𝐧𝐞𝐭𝐢𝐜 𝐬𝐞𝐜𝐫𝐞𝐭𝐬 𝐨𝐟 𝐩𝐥𝐚𝐧𝐭 𝐭𝐡𝐚𝐭 𝐥𝐢𝐯𝐞𝐬 𝐟𝐨𝐫 𝐭𝐡𝐨𝐮𝐬𝐚𝐧𝐝𝐬 𝐨𝐟 𝐲𝐞𝐚𝐫𝐬
‘It's just a really super weird thing,’ says plant geneticist Andrew Leitch If you want to understand the science of longevity and perseverance, you can't do much better than the Welwitschia plant. Considered one of the toughest and longest-living plants, a Welwitschia can survive for thousands of years in the bone-dry deserts of southern Africa. And as long as it's alive, it never stops growing. That's why scientists have studied the DNA of the Welwitschia, in the hopes of unlocking the secrets of its incredible ability to survive for millennia in extremely inhospitable conditions. "It's just a really super weird...
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