Regenerative Medicine,Psilocybin & Depression, and Stem Cell Therapy for Chronic Health Issues | Dr. Adeel Khan | EP 409

Regenerative medicine, including the use of stem cells, PRP, and exosomes, offers promising potential for treating chronic health problems and has shown incredible results in addressing various conditions 

Questions to inspire discussion 

• What is regenerative medicine?

  —Regenerative medicine involves using stem cells, PRP, and exosomes to treat chronic health problems and degenerative diseases.

• How can stem cells be used for treatment?

  —Stem cells can be derived from various sources and have the ability to repair and regenerate tissue, offering potential alternative treatments for various conditions.

• What are the potential risks of stem cell therapy?

  —While mesenchymal stem cells can repair tissue without causing reactions in certain people, cancer cells lose the ability to stop replicating and can lead to tumors.

• What are the potential benefits of exosomes?

  —Exosomes can signal the body to start healing and regenerating damaged tissue, and can be used to repair and regenerate skin and other tissues.

• How is regenerative medicine being used to treat chronic diseases?

  —Regenerative medicine aims to use customized cell and gene therapy to treat chronic diseases, shifting from traditional prescription drugs to real solutions that can put people into remission.

Key Insights

Advancements in Regenerative Medicine

• 👩‍⚕️ Dr. Adeel Khan's successful treatment for chronic osteoarthritic condition using regenerative medicine shows promising potential for addressing chronic health problems.
• 🩺 Regenerative medicine, including the use of stem cells, PRP, and exosomes, aims to repair tissue back to a previous state, offering hope for those suffering from chronic pain without the risks of addiction and surgery.
• 🧠 The learning curve for distinguishing tears and lesions in radiology is steep, requiring specialized training and thousands of hours of exposure to image data.
• 🏥 Instead of giving pills for chronic disease, the shift is towards giving customized cells as a real solution to treat the root cause and put people into remission.
• 🔬 The use of chimeric antigen receptor in T cells to target and kill hyperproliferative B cells in lupus patients is a fascinating and effective approach in immunotherapy.
• 💉 The next generation of cell therapy will allow for custom cell lines for almost every medical condition like diabetes, cancer, and dementia.
• 🩺 Fecal transplant pills can have a huge impact on the body and may be used for anti-aging and longevity, extending lifespan by 30% in mice.
• 🧠 Chronic depression is an inflammatory condition, and there is evidence that SSRIs work because they are anti-inflammatory, not just because of their neurochemical consequences.
• 🔬 Using intravenous exosomes to reduce neural inflammation and cross the blood brain barrier could be a promising approach in treating neurological disorders.
• 🩺 Dr. Adeel Khan has treated hundreds of people with a particular intervention, seeing incredible changes in individuals suffering from conditions like panic attacks.

Cutting-Edge Techniques in Gene Therapy

• 🧠 Gene edited stem cells, created from induced pluripotent stem cells, offer a promising approach to treating complex conditions like Multiple Sclerosis.
• 🩺 The next generation of stem cells, specifically designed for osteoarthritis, are ipsc derived and gene edited to overexpress certain transcription factors, marking a significant advancement in the field.
• 🧬 Minicircle vector technology is a safer alternative to CRISPR for gene therapy, with more accuracy and fewer off-site targets.

Innovative Approaches in Mental Health Treatment

• 🧠 The use of psilocybin to treat depression and anxiety could potentially address unresolved childhood trauma and decrease trait neuroticism, leading to a major discovery in mental health treatment.
• 🧠 The combination of psilocybin therapy and physiological intervention has been impactful in treating depression and PTSD, shifting people from being suicidal to not being suicidal anymore.

#Health #MentalHealth #JordanBPeterson #Psychology #AdeelKhan

Clips 

• 00:00 🧬 Dr. Adeel Khan discusses the potential of genetic reprogramming and regenerative medicine for treating chronic health problems, including the use of stem cells and ultrasound for chronic pain and tissue damage.
  • Dr. Adeel Khan discusses the potential of genetic reprogramming and regenerative medicine for treating chronic health problems such as depression, chronic pain, and degenerative diseases.
  • Dr. Khan discusses the use of regenerative medicine, including stem cells and ultrasound, to treat chronic pain and tissue damage.
  • Wealthy businessman with chronic shoulder pain for 15 years found relief through diagnostic Dynamic ultrasound and treatment by Dr. Adeel Khan, who learned from the best in the field.
  • The speaker discusses the development of a machine learning neural net to detect tears and guide physicians, as well as the use of exosomes for treatment.
  • Stem cells, specifically mesenchymal stem cells, can be derived from various sources such as umbilical cord tissue and have the ability to repair and regenerate tissue, offering a potential alternative to controversial embryonic stem cells.
  • Stem cells have the potential to differentiate into specific cells, but cancer cells lose the ability to stop replicating and can lead to tumors, while mesenchymal stem cells can repair tissue without the risk of causing reactions in certain people.
• 13:02 🔬 Stem cells and exosomes have the potential to heal and regenerate damaged tissue, with gene-edited stem cells and regenerative medicine offering real solutions for chronic diseases and promising results in treating cancer.
  • Stem cells and exosomes signal to the body to start healing and regenerating damaged tissue, and can be used to repair and regenerate skin and other tissues.
  • Intravenous stem cells and exosomes are being used for a variety of conditions, with stem cells having a strong immunomodulatory effect and potential for treating autoimmune conditions, while gene-edited stem cells are being developed for treating multiple sclerosis.
  • The body has the ability to revert to an earlier stage of development and progress forward again, with immune cells and stem cells showing variability and potential for earlier forms, and even junk DNA storing additional information for this process.
  • Regenerative medicine aims to use customized cell and gene therapy to treat chronic diseases, shifting from traditional prescription drugs to real solutions that can put people into remission.
  • Gene edited car te-cells were used in a trial in Germany to treat lupus, resulting in remission for all participants, even after a year follow-up.
  • Cell and gene therapies, such as CAR T and CAR NK, show promising results in treating cancer, but regulatory bodies in North America are making it difficult for these therapies to be approved, while Japan has been using them for over 10 years.
• 24:30 🔬 Pharmaceutical companies' influence on healthcare system hinders regenerative medicine innovation, while alternative medicine and ancient Greek health approaches offer potential solutions.
  • Exodus 90 is a 90-day program designed to help men find purpose and improve their lives, with reported benefits including decreased phone usage, stronger marriages, and a more meaningful relationship with God.
  • Pharmaceutical companies in the US have a lot of influence on doctors and the healthcare system, leading to a lag in regenerative medicine innovation compared to Japan.
  • Pharmaceutical companies' marketing to consumers and influence on physician education has led to high prices for new medical interventions, making it difficult for physicians to break free from the system and focus on prevention and finding cures.
  • Cheap and effective pharmaceuticals for treating various conditions are often not widely known or marketed because there is no profit incentive for the pharmaceutical industry.
  • The speaker discusses the challenges of making dietary recommendations for prevention, the lack of emphasis on nutrition in medical school, and the potential of alternative medicine in treating chronic diseases.
  • Ancient Greeks had a multi-dimensional approach to health at the Temple of Asclepius, incorporating drama, exercise, and healing visions, which is more sophisticated than modern approaches to disease.
• 34:39 🔬 Building resiliency in people's bodies through gene therapy can help combat the broken US healthcare system and promote healthy living without drastic lifestyle changes, while regenerative medicine and alternative treatments like stem cells are important in treating chronic diseases.
  • The US healthcare system is broken, with excessive spending and poor health outcomes, and the environment promotes unhealthy eating habits leading to high obesity rates.
  • Building resiliency in people's bodies through gene therapy is a way to help them benefit from healthy living without having to make drastic lifestyle changes, which can be difficult for people to do.
  • Low socio-economic status is the best predictor of long-term health, and diets involving chronic calorie restriction often lead to failure and eating disorders, while developing a healthy relationship with food requires cognitive behavioral therapy and a lot of work.
  • The speaker discusses their transition from being a personal trainer to medical school, their disillusionment with the traditional medical system, and their desire to find alternative ways to treat chronic diseases.
  • Surgical specialties often deal with end-stage lifestyle-related diseases, leading the speaker to pursue sports medicine and alternative treatments like platelet-rich plasma and stem cells for healing.
  • The speaker discusses the importance of regenerative medicine and the difference between physicians and scientists in evaluating scientific research.
• 45:15 🔬 Medical knowledge is rapidly advancing, with regenerative medicine practices and stem cell therapy showing potential in treating chronic diseases and complex conditions like Parkinson's.
  • Medical knowledge is doubling every 73 days, making it impossible to keep up, and there is a 15-20 year gap in implementing new treatments for patients.
  • Chronic disease and suffering, particularly chronic pain, have a significant impact on mental health and society, and regenerative medicine practices are being used to address these issues by targeting the hallmarks of aging that govern most chronic diseases.
  • Early cellular changes in diseases can go undetected by traditional diagnostics, leading to the need for alternative treatments like stem cell therapy, but the field is plagued by illegal clinics and lack of expertise.
  • Dr. Adeel Khan discusses the potential of stem cell therapy in treating various medical conditions and the possibility of it becoming more accessible and covered by insurance in the future.
  • Stem cell research can be used to treat advanced stages of osteoarthritis by targeting inflammation and regrowing cartilage, with the development of second generation stem cells specifically for osteoarthritis.
  • Dr. Adeel Khan discusses treating chronic complex conditions with a combination of systemic intravenous stem cells, peptide protocols, and FMT pills to restore the immune system and treat diseases like Parkinson's.
• 58:35 🧠 Fecal transplant pills can impact the body, training the immune system is crucial, depression is linked to inflammation, and various treatments can address psychiatric diseases and nervous system disorders.
  • Fecal transplant pills can have a huge impact on the body, can be used for anti-aging and longevity, and can be beneficial for children and toddlers who have been exposed to antibiotics or born via C-section.
  • Properly training the immune system at a young age is crucial to preventing chronic diseases, and overuse of antibiotics can lead to immune dysfunction.
  • Depression is not a single condition, but rather a result of various medical, physical, and lifestyle factors, with evidence suggesting that chronic depression is an inflammatory condition and that treatments like SSRIs and statins work by reducing inflammation and addressing gut-brain axis issues.
  • Interventional physician discusses reducing neural inflammation using intravenous exosomes to help with symptoms of brain inflammation and nervous system disorders.
  • Psychiatrist discusses using dietary manipulations and exosome treatment to address physiological basis of psychiatric diseases, as well as addressing unresolved emotional trauma through interventions like Stell ganglion block.
  • Dr. Adeel Khan discusses the use of peptides and anesthetic injections to calm the Vegas nerve and remodulate signaling, leading to a dramatic effect on the nervous system and improved resilience to stress.
• 01:06:02 🧠 Evaluate life dimensions for depression, exosomes and Vegas nerve treatments show promise, childhood trauma can trigger depression and anxiety, and psilocybin may decrease neuroticism and increase resilience.
  • Evaluate the dimensions of life to identify depression and consider physiological factors in the diagnostic process.
  • Exosomes could be particularly effective for people suffering from depression and chronic illness, and the effectiveness of anti-depressants is impacted by the proper diagnostic categories.
  • Canadian military is interested in using Vegas nerve and Stell ganglion block treatments for veterans with PTSD, as traditional medications and therapy have not been effective.
  • The speaker discusses a procedure involving injecting anesthetic and peptides to suppress sympathetic overdrive and modulate the vagus nerve, resulting in a dramatic improvement in the patient's well-being.
  • Psychiatric disorders are often positive feedback loops that can be broken with interventions, and hundreds of people have been treated with success.
  • Childhood trauma can trigger depression and anxiety, and using treatments like psilocybin can potentially decrease trait neuroticism and increase emotional resilience.
• 01:15:33 🔬 Combining psilocybin therapy with physiological intervention shows promise in treating depression, while gene therapy and cell therapy offer potential for treating chronic illnesses and regrowing cartilage.
  • Combining psilocybin therapy with physiological intervention has shown positive effects in treating depression and PTSD, but caution is needed to avoid overinterpreting anecdotal evidence.
  • Dr. Adeel Khan discusses the importance of multimodal interventions in improving patient health, and the potential of reversible plasma gene therapy in clinical trials for treating refractory patients.
  • Gene therapy using a peptide called fallatin has shown potential to inhibit myostatin, increase muscle mass, reduce systemic inflammation, and potentially reverse biological aging, with a phase two trial set to start in 2024.
  • Dr. Adeel Khan discusses the intersection of gene therapy, cell therapy, and tissue engineering for regrowing cartilage, the use of disruptive models for faster trials, and the integration of business vision into medical practices to help more people.
  • The speaker discusses the potential of gene and cell therapies, as well as the use of stem cells and natural killer cells to treat chronic illnesses caused by toxic mold and fungal infections.
  • Biology is advancing rapidly, and people should seek information from academic scientists to understand the potential of cell and gene therapy in medicine 4.0 for longevity and improved quality of life.

------------------------------------- 1:35:18 2023-12-30T19:30:24Z